Which of the following laboratory findings is most consistent with diabetes insipidus?

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Multiple Choice

Which of the following laboratory findings is most consistent with diabetes insipidus?

Explanation:
Diabetes insipidus makes the kidneys unable to concentrate urine, so the urine becomes very dilute due to lack of ADH effect. This shows up as a very low urine specific gravity. Among the options, 1.001 to 1.003 is the most dilute, matching the pattern of DI. The other ranges indicate urine that is more concentrated or closer to normal, which would not fit DI. In DI you’d also expect serum osmolality to rise and possibly hypernatremia if fluid loss continues, reinforcing the diagnosis.

Diabetes insipidus makes the kidneys unable to concentrate urine, so the urine becomes very dilute due to lack of ADH effect. This shows up as a very low urine specific gravity. Among the options, 1.001 to 1.003 is the most dilute, matching the pattern of DI. The other ranges indicate urine that is more concentrated or closer to normal, which would not fit DI. In DI you’d also expect serum osmolality to rise and possibly hypernatremia if fluid loss continues, reinforcing the diagnosis.

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